Abuse and diversion of buprenorphine sublingual tablets and film
نویسندگان
چکیده
منابع مشابه
Efficacy of Buprenorphine/Naloxone Rapidly Dissolving Sublingual Tablets (BNX-RDT) After Switching From BNX Sublingual Film
OBJECTIVES The aim of the study was to evaluate treatment retention, efficacy, and preference ratings among opioid-dependent patients transitioning between a buprenorphine/naloxone rapidly dissolving sublingual tablet formulation (BNX-RDT) and BNX film. METHODS After a 2-day, blinded, fixed-dose induction with BNX-RDT (5.7/1.4 mg and 5.7/1.4 or 11.4/2.8 mg, respectively) or buprenorphine (8 m...
متن کاملBuprenorphine Use and Risk of Abuse and Diversion
Opioid dependence is a chronic relapsing disorder with an excess mortality rate [1-4]. Over than 90% of the estimates relate to heroin, as demonstrated in a global literature review by Degenhardt et al. [5]. Opioid maintenance treatment has proven efficacy in reducing opioid consumption and psychosocial and medical morbidity and in increasing treatment retention rates and social functioning in ...
متن کاملPost marketing surveillance of sublingual buprenorphine naloxone combination tablets.
BACKGROUND & OBJECTIVES A combination of buprenorphine-naloxone (Addnok-N) tablets has been recently introduced in India as treatment for Opioid dependence. This study was undertaken to evaluate the possible adverse consequences following use of the buprenorphine-naloxone tablets through post marketing surveillance. METHODS National Drug Dependence Treatment Centre (NDDTC), AIIMS, India, moni...
متن کاملPost-operative Analgesia in Opioid Dependent Patients: Comparison of Intravenous Morphine and Sublingual Buprenorphine
Background: Acute and chronic pain is prevalent in patients with opioid dependence. Lack of knowledge concerning the complex relationship between pain, opioid use, and withdrawal syndrome can account for the barriers encountered for pain management. This study was designed to evaluate the efficacy of sublingual (SL) buprenorphine for post-operative analgesia, compared with intravenous (IV) morp...
متن کاملBuprenorphine implants for treatment of opioid dependence: randomized comparison to placebo and sublingual buprenorphine/naloxone.
AIMS To evaluate the safety and efficacy of buprenorphine implants (BI) versus placebo implants (PI) for the treatment of opioid dependence. A secondary aim compared BI to open-label sublingual buprenorphine/naloxone tablets (BNX). DESIGN Randomized, double-blind, placebo-controlled trial. Subjects received either four buprenorphine implants (80 mg/implant) (n = 114), four placebo implants (n...
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ژورنال
عنوان ژورنال: Journal of Substance Abuse Treatment
سال: 2014
ISSN: 0740-5472
DOI: 10.1016/j.jsat.2014.02.003